Modern organized religion is based predominantly on secondary religious experience--we read about others' extraordinary direct spiritual encounters in the distant past and have faith that God is out there. Yet what if powerful sacraments existed to help us directly experience the sacred? What if there were ways to seek out the meaning of being human and our place in the universe, to see the sacred in the world that surrounds us?

In this book, more than 25 spiritual leaders, scientists, and psychedelic visionaries examine how we can return to the primary spiritual encounters at the basis of all religions through the guided use of entheogens. With contributions by Albert Hofmann, Huston Smith, Stanislav Grof, Charles Tart, Alexander "Sasha" Shulgin, Frances Vaughan, Myron Stolaroff, and many others, this book explores protocols for ceremonial use of psychedelics, the challenges of transforming entheogenic insights into enduring change, psychoactive sacraments in the Bible, myths surrounding the use of LSD, and the transformative ayahuasca rituals of Santo Daime. It also includes personal accounts of Walter Pahnke's Good Friday Experiment as well as a 25-year follow-up with its participants. Dispelling fears of inauthentic spirituality, addiction, and ill-prepared encounters with the holy, this book reveals the potential of entheogens as catalysts for spiritual development, a path through which faith can directly encounter God's power, and the beginning of a new religious era based on personal spiritual experience.