Propofol
COMMON & BRAND NAMES
Diprivan
EFFECTS CLASSIFICATION
Sedative
CHEMICAL NAME
2,6-Diisopropylphenol
DESCRIPTION
Propofol is a short-acting sedative-hypnotic used in clinical settings for general anesthesia or monitored sedation during medical procedures or intensive care. It received significant media attention after its involvement in Michael Jackson's death. It has a steep dose-response curve.
EXPERIENCES #
Riding into Unconsciousness, by clippy
Total Blackout, by Lampmann
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OFF-SITE RESOURCES
PRIMARY RESOURCES #
FDA Alert on Propofol (2007)
MEDIA COVERAGE #
With High-Profile Death, Focus on High-Risk Drug - NYTimes, Aug 7 2009
Alert on M.D. abuse of Jackson drug - Wall Street Journal, Aug 6 2009
Doctors familiar with death by propofol - LA Times, Aug 4 2009
Abuse of drug used by Michael Jackson growing among medical professionals - Guardian UK, Jul 31 2009
DEA might tighten restrictions on sedative drug - CNN Health, Jul 15 2009
Sedative could be deadly in people with seizures - Forbes, Oct 27 2008
Increase in sedation raises eyebrows - Columbus Dispatch, Sep 26 2006
Fish oil could hold key to cancer drug breakthrough - Business Wire, Jun 8 2005
Manhattan Pharmaceuticals To present safety data for propofol lingual spray - Business Wire, Mar 15 2005
Propofol sedation faces obstacles - Internal Medicine News, Dec 1 2004
FDA issues warning on propofol - CMAJ, May 29 2001