Mimosa hostilis is not a controlled species in the United States. Live plants and seeds are often sold and grown. However, DMT, one of the chemicals contained in the plant, is Schedule I in the U.S. Practically, this means that if an extraction is done on DMT containing Mimosa species, the resulting DMT is illegal to possess. We are unaware of any cases in which an individual has been prosecuted simply for growing a plant or for doing a home extraction of a plant, although it seems quite possible that a few such cases exist.

Large scale (especially commercial) extraction of DMT from Mimosa species falls into the realm of "clearly illegal" and would very likely be prosecuted. It is also quite possible that importation of DMT containing Mimosa species into the United States could result in problems with customs, especially if large volumes are imported.