Arundo donax is not a controlled species in the United States. Live plants and seeds are often sold and grown. However, DMT, one of the chemicals contained in the plant, is Schedule I in the U.S. Practically, this means that if an extraction is done on DMT-containing Arundo donax, the resulting DMT is illegal to possess. We are unaware of any cases in which an individual has been prosecuted simply for growing a plant or for doing a home extraction of a plant, although it seems quite possible that a few such cases exist.

Large scale (especially commercial) extraction of DMT from plants falls into the realm of "clearly illegal" and would very likely be prosecuted.