Psilocybe cubensis is a medium strength psilocybian mushroom consisting of approximately .63% psilocybin and .60% psilocin in dried wild mushrooms. Indoor cultivated mushrooms tend to have higher concentrations. Note that potency of mushrooms can vary greatly from one batch to the next and from one part of a single mushroom to another part (cap and stem can have different concentrations). Because of these natural variations, chopping or grinding up multiple mushrooms and homogeninizing the material can help reduce the risk of unexpectedly strong (or weak) doses of psilocybin.

The following chart shows approximate oral dosages for common (dried) Psilocybe cubensis in grams. P. cubensis and other psilocybin mushrooms can vary in potency by as much as 10x.

Oral P. cubensis Dosages Threshold .25 g 1/100 oz Light .25 - 1 g 1/100 - 1/28oz Common 1 - 2.5 g 1/28 - 1/10oz Strong 2.5 - 5 g 1/10 - 1/6oz Heavy 5 + g 1/6oz +

Onset : 10 - 40 minutes (when chewed and held in mouth) Onset : 20 - 60 minutes (when swallowed on empty stomach) Duration : 2 - 6 hours Normal After Effects : up to 8 hours

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Comparative potency of selected Psilocybe mushrooms, Stamets 1996

Extraction and analysis of indole derivatives from fungal biomass, Gartz 1994

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Psychedelics Encyclopedia, by Peter Stafford
Psilocybin Mushrooms of the World, Paul Stamets