Erowid References Database
Glennon RA, Martin B, Johnson KM, End D.
“7,N,N-Trimethyltryptamine: a selective inhibitor of synaptosomal serotonin uptake”.
Res Commun Chem Pathol Pharmacol. 1978 Jan 17;19(1):161-4.
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Abstract
7,N,N-Trimethyltryptamine (TMT) was synthesized and evaluated as an inhibitor of synaptosomal biogenic amine uptake in rat forebrain homogenates. In addition to inhibiting 3H-serotonin uptake (IC50 = 0.4 micrometer), TMT appears to be quite selective and is much less potent in blocking either 3H-norepinephrine or 3H-dopamine uptake (IC50 = 180 micrometer and 61 micrometer, respectively).
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